Generic names: High-Dose Quadrivalent (Influenza Vaccine) Suspension for intramuscular injection.
Indication and Usage: The FDA has approved this vaccine for active immunization for the prevention of influenza disease caused by influenza A subtype viruses and type B viruses contained in the vaccine. Fluzone + Fluad High-Dose Quadrivalent is approved for use in persons 65 years of age and older.
Fluzone High-Dose Quadrivalent for intramuscular injection is an inactivated influenza vaccine, prepared from influenza viruses propagated in embryonated chicken eggs. The virus-containing allantoic fluid is harvested and inactivated with formaldehyde.
FLUAD QUADRIVALENT (Influenza Vaccine, Adjuvanted), a sterile injectable emulsion for intramuscular use, is a quadrivalent, inactivated influenza vaccine prepared from virus propagated in the allantoic cavity of embryonated hens’ eggs inoculated with a specific type of influenza virus.
Manufacturer-listed adverse reactions:
Fluzone High-Dose Quadrivalent can cause: Thrombocytopenia, Lymphadenopathy, Anaphylaxis, Urticaria (hives), Angioedema (swelling), Ocular hyperemia, Guillain-Barré syndrome, Rhinorrhea (runny nose), Febrile convulsions, Optic neuritis/neuropathy, Brachial neuritis, Syncope (fainting), Vomiting, Vasculitis, Stevens-Johnson syndrome, Paresthesia (skin crawling), Myelitis (including encephalomyelitis and transverse myelitis), Dyspnea (shortness of breath), Facial palsy (Bell’s palsy), Pruritus (itchy Skin), Asthenia/fatigue, Chest pain, Chills, Dizziness, Vasodilatation, Cough, Wheezing, Throat tightness, Oropharyngeal pain, Convulsions.
Fluad Quadrivalent can cause: Thrombocytopenia (some cases were severe with platelet counts less than 5,000 per mm3), Lymphadenopathy, Extensive swelling of injected limb lasting more than one week, Injection site cellulitis-like reactions (some cases of swelling, pain, and redness extending more than 10 cm and lasting more than 1 week), Anaphylactic shock, Anaphylaxis, Angioedema (swelling), Encephalomyelitis, Guillain-Barré Syndrome, Convulsions, Neuritis, Neuralgia, Paraesthesia (skin crawling), Syncope (fainting), Presyncope (feeling faint), Erythema multiforme, Urticaria (hives), Pruritis (itchy skin), Non-specific rash, Vasculitis, Renal vasculitis, and Muscular weakness.
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For Fluzone alternatives, please visit the Flu webpage.