Trade name: Lupron Depot – Ped
Generic names: Leuprolide acetate
Indication and Usage: FDA has approved this injection for the treatment of children with central precocious puberty. This is used off label (not according to manufacturer guidance) as a hormone blocker.
Manufacturer-listed adverse reactions | Lupron can cause: Rash/urticaria (hives)/photosensitivity, Localized reactions at injection site including induration and abscess, Hypotension, Decreased WBC (white blood cells), Peripheral neuropathy, Convulsion, Spinal fracture/paralysis, Tenosynovitis-like symptoms (inflammation of the membrane surrounding tendons), Prostate pain, Pituitary apoplexy (sudden headache, vomiting, visual changes, ophthalmoplegia, altered mental status, and sometimes cardiovascular collapse. Immediate medical attention has been required), Symptoms consistent with fibromyalgia (e.g., joint and muscle pain, headaches, sleep disorders, gastrointestinal distress, and shortness of breath) have been reported individually and collectively, Pulmonary embolism (blockage of an artery in the lungs by a substance that has moved from elsewhere in the body through the bloodstream), Hepatic (liver) dysfunction, Hair growth, Hearing disorder, Hard nodule in throat, Weight gain, Increased uric acid, Respiratory disorders, Decreased bone density, Mood swings, Depression, Suicidal ideation and attempt, Myocardial infarction (heart attack), Interstitial lung disease, Serious drug-induced liver injury, Diabetes
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Lupron Depot – Ped can cause: Rash/urticaria (hives)/photosensitivity, Localized reactions at injection site including induration and abscess, Hypotension, Decreased WBC (white blood cells), Peripheral neuropathy, Convulsion, Spinal fracture/paralysis, Tenosynovitis-like symptoms (inflammation of the membrane surrounding tendons), Prostate pain, Pituitary apoplexy (sudden headache, vomiting, visual changes, ophthalmoplegia, altered mental status, and sometimes cardiovascular collapse. Immediate medical attention has been required), Symptoms consistent with fibromyalgia (e.g., joint and muscle pain, headaches, sleep disorders, gastrointestinal distress, and shortness of breath) have been reported individually and collectively, Pulmonary embolism (blockage of an artery in the lungs by a substance that has moved from elsewhere in the body through the bloodstream), Hepatic (liver) dysfunction, Hair growth, Hearing disorder, Hard nodule in throat, Weight gain, Increased uric acid, Respiratory disorders, Decreased bone density, Mood swings, Depression, Suicidal ideation and attempt, Myocardial infarction (heart attack), Interstitial lung disease, Serious drug-induced liver injury, Diabetes
