Trade name: PNEUMOVAX® 23
Generic names: Pneumococcal vaccine polyvalent Sterile, Liquid Vaccine for Intramuscular or Subcutaneous Injection
Indication and Usage: PNEUMOVAX 23 is a vaccine indicated for active immunization for the prevention of pneumococcal disease caused by the 23 serotypes contained in the vaccine (1, 2, 3, 4, 5, 6B, 7F, 8, 9N, 9V, 10A, 11A, 12F, 14, 15B, 17F, 18C, 19F, 19A, 20, 22F, 23F, and 33F). (1.1) PNEUMOVAX 23 is approved for use in persons 50 years of age or older and persons aged ≥2 years who are at increased risk for pneumococcal disease.
Ingredients: Each 0.5-mL dose of vaccine contains 25 micrograms of each polysaccharide type in isotonic saline solution containing 0.25% phenol as a preservative. The vaccine is used directly as supplied. No dilution or reconstitution is necessary.
Manufacturer-listed adverse reactions | PPSV23 (Pneumovax® 23) can cause: Cellulitis, Malaise (weakness), Fever (>102°F), Warmth at the injection site, Decreased limb mobility, Peripheral edema (swelling) in the injected extremity, Nausea / Vomiting, Lymphadenopathy, Lymphadenitis, Thrombocytopenia in patients with stabilized idiopathic thrombocytopenic purpura, Increased serum C-reactive protein, Hemolytic anemia in patients who have had other hematologic disorders, Leukocytosis, Anaphylactoid reactions, Serum Sickness, Angioneurotic edema, Arthralgia (joint stiffness), Arthritis, Paresthesia (skin crawling), Radiculoneuropathy (pinched nerve), Guillain-Barré syndrome, Febrile convulsions, Rash / Urticaria (hives), Cellulitis-like reactions, Erythema multiforme.
Limitations of Use: PNEUMOVAX 23 will not prevent disease caused by capsular types of pneumococcus other than those contained in the vaccine.
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