Trade name: SHINGRIX
Generic names: Zoster Vaccine Recombinant, Adjuvanted suspension for intramuscular injection
Indication and Usage: SHINGRIX is a vaccine indicated for prevention of herpes zoster (HZ) (shingles):
- in adults aged 50 years and older.
- in adults aged 18 years and older who are or will be at increased risk of HZ due to immunodeficiency or immunosuppression caused by known disease or therapy.
Ingredients: Each 0.5-mL dose is formulated to contain 50 mcg of the recombinant gE antigen, 50 mcg of MPL, and 50 mcg of QS-21. Each dose also contains 20 mg of sucrose (as stabilizer), 4.385 mg of sodium chloride, 1 mg of DOPC, 0.54 mg of potassium dihydrogen phosphate, 0.25 mg of cholesterol, 0.160 mg of sodium dihydrogen phosphate dihydrate, 0.15 mg of disodium phosphate anhydrous, 0.116 mg of dipotassium phosphate, and 0.08 mg of polysorbate 80. Each dose may also contain residual amounts of host cell proteins (≤3.0%) and DNA (≤2.1 picograms) from the manufacturing process.
Manufacturer-listed adverse reactions: Shingrix (recombinant) can cause: Angioedema, Rash, Urticaria (hives), Decreased mobility of the injected arm which may persist for 1 or more weeks, Gastrointestinal symptoms, Myalgia, Fatigue, Shivering, Fever, Guillain-Barré Syndrome, Syncope: visual disturbance, paresthesia, and tonic-clonic limb movements.
Limitations of Effectiveness: SHINGRIX is not indicated for prevention of primary varicella infection (chickenpox).
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Looking for Shingles Vaccine alternatives? Here are some to research.
Disclaimer: This guide is for informational purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. May contain affiliate links. Product photos/descriptions provided by company websites. This is not medical advice.
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