Generic names: Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine Adsorbed) Suspension for Intramuscular Injection, Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine, Adsorbed) injectable suspension for intramuscular use
Indication and Usage:
Adacel is a vaccine indicated for:
- active booster immunization against tetanus, diphtheria and pertussis. Adacel is approved for use in persons 10 through 64 years of age.
- immunization during the third trimester of pregnancy to prevent pertussis in infants younger than 2 months of age.
BOOSTRIX is a vaccine indicated for:
- active booster immunization against tetanus, diphtheria, and pertussis in individuals aged 10 years and older.
- immunization during the third trimester of pregnancy to prevent pertussis in infants younger than 2 months of age.
Ingredients:
Adacel is a sterile isotonic suspension of tetanus and diphtheria toxoids and pertussis antigens adsorbed on aluminum phosphate, for intramuscular injection. Each 0.5 mL dose contains 5 Lf tetanus toxoid (T), 2 Lf diphtheria toxoid (d), and acellular pertussis antigens [2.5 mcg detoxified pertussis toxin (PT), 5 mcg filamentous hemagglutinin (FHA), 3 mcg pertactin (PRN), 5 mcg fimbriae types 2 and 3 (FIM)]. Other ingredients per 0.5 mL dose include 1.5 mg aluminum phosphate (0.33 mg aluminum) as the adjuvant, ≤5 mcg residual formaldehyde, <50 ng residual glutaraldehyde and 3.3 mg (0.6% v/v) 2-phenoxyethanol (not as a preservative). The antigens are the same as those in DAPTACEL; however, Adacel is formulated with reduced quantities of diphtheria and detoxified PT.
BOOSTRIX (Tetanus Toxoid, Reduced Diphtheria Toxoid and Acellular Pertussis Vaccine,
Adsorbed) is a noninfectious, sterile, vaccine for intramuscular administration. It contains tetanus
toxoid, diphtheria toxoid, and pertussis antigens (inactivated pertussis toxin [PT] and
formaldehyde-treated FHA and PRN). The antigens are the same as those in INFANRIX, but
BOOSTRIX is formulated with reduced quantities of these antigens. Each 0.5-mL dose contains aluminum hydroxide as adjuvant (formulated to contain 0.3 mg aluminum) and 4.4 mg of sodium chloride. The aluminum content is measured by assay. Each dose also contains ≤100 mcg of residual formaldehyde and ≤100 mcg of polysorbate 80 (Tween 80).
Manufacturer-listed adverse reactions |
TDAP (Adacel) can cause: Anaphylactic reaction, Guillain-Barré syndrome, Facial palsy, Syncope (Fainting), Myelitis, Myocarditis, Urticaria (Hives), Angioedema, Edema (Swelling), Rash, Hypotension (Low blood pressure), Hypoesthesia (Numbness), Convulsion, Pruritus (Itchy skin), Myositis, Muscle spasm, Large injection site reactions, Extensive limb swelling from the injection site beyond one or both joints, Injection site bruising, Sterile abscess (Pus), Arthus hypersensitivity, Brachial neuritis, Paresthesia.
TDAP (Boostrix) can cause: Encephalitis (Brain inflammation), Loss of consciousness, Exanthem, Henoch-Schönlein purpura, Lymphadenitis, Lymphadenopathy, Allergic reactions, anaphylactic and anaphylactoid reactions, Myocarditis, Extensive swelling of the injected limb, Arthralgia (Joint pain), Injection site induration, inflammation, mass, pruritus, nodule, warmth, reaction, Back pain, Myalgia (Muscle pain), Convulsions (with and without fever), Facial palsy, Paresthesia (Skin crawling), Syncope (Fainting), Angioedema, Rash, Urticaria (hives).
Need more info? Click the link below for a helpful infographic you can view + save on your device.
Looking for TDAP alternatives? Here are some to research.
Disclaimer: This guide is for informational purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. May contain affiliate links. Product photos/descriptions provided by company websites. This is not medical advice.
The alternative to the TDAP vaccine is to not accept it and treat the conditions naturally when needed. Here are some things to research:
Pertussis FAQ
Do you worry about pertussis and have been recommended the TDAP or DTAP vaccines? Click the image above for prevention and treatment protocols + products to research for educated and empowered medical decisions.
Diphtheria FAQ
Do you worry about diphtheria and have been recommended the Tetanus, TDAP, or DTAP vaccines? Click the image above for prevention and treatment protocols + products to research for educated and empowered medical decisions.
Tetanus FAQ
Do you worry about tetanus and have been recommended the Tetanus vaccine? Click the image above for prevention and treatment protocols + products to research for educated and empowered medical decisions.