Zoloft

Trade name: Zoloft

Generic name: sertraline hydrochloride tablets

Indication and Usage: The FDA has approved this drug as a selective serotonin reuptake inhibitor (SSRI) for the treatment of:

• Major depressive disorder (MDD)
• Obsessive-compulsive disorder (OCD)
• Panic disorder (PD)
• Post-traumatic stress disorder (PTSD)
• Social anxiety disorder (SAD)
• Premenstrual dysphoric disorder (PMDD)

Ingredients: sertraline hydrochloride, dibasic calcium phosphate dihydrate, D&C Yellow #10 aluminum lake (in 25 mg tablet), FD&C Blue #1 aluminum lake (in 25 mg tablet), FD&C Red #40 aluminum lake (in 25 mg tablet), FD&C Blue #2 aluminum lake (in 50 mg tablet), hydroxypropyl cellulose, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80, sodium starch glycolate, synthetic yellow iron oxide (in 100 mg tablet), and
titanium dioxide.

Manufacturer-listed adverse reactions | Zoloft can cause: Increased coagulation times (altered platelet function), AV (Atrioventricular) block, Bradycardia (slow heart rate), Atrial arrhythmias (irregular heart beat), QT-interval prolongation (heart muscle takes longer than normal to recharge between beats), Ventricular tachycardia (including Torsade de Pointes – abnormal heart rhythm that can lead to sudden cardiac death), Angioedema (swelling), Hyponatremia, Hyperglycemia, Serotonin syndrome, Extrapyramidal symptoms:, Akathisia (inner restlessness accompanied by mental distress and an inability to sit still), Decreased libido, Dystonia (twisting and repetitive movements or abnormal fixed postures), Oculogyric crisis (prolonged involuntary upward deviation of the eyes), Psychosis (difficulty determining what is real and what is not real), Paroniria (excess of morbid dreams and nightmares), Photosensitivity skin reaction and other severe cutaneous reactions, which potentially can be fatal, such as Stevens-Johnson Syndrome (SJS) and toxic epidermal necrolysis (TEN), Vasculitis (group of disorders that destroy blood vessels by inflammation), Pancreatitis, Optic neuritis, Tachycardia (increased heart rate), Tinnitus (ringing in the ears), Hypothyroidism, Mydriasis (dilated pupils), Blurred vision, Hematochezia (passage of fresh blood through the anus), Melena (dark black, tarry feces), Rectal hemorrhage, Severe liver events (including hepatitis, jaundice, liver failure with some fatal outcomes), Aplastic anemia (body fails to produce blood cells in sufficient numbers), Pancytopenia, Leukopenia, Thrombocytopenia, Lupus-like syndrome, Serum sickness, Gynecomastia (abnormal non-cancerous enlargement of one or both breasts in males), Cerebrovascular spasm (including reversible cerebral vasoconstriction syndrome and CallFleming syndrome), Angle-Closure Glaucoma (damage to the optic nerve and potential vision loss), Activation of mania/hypomania for bipolar patients, Nausea, Diarrhea/loose stool, Tremor, Dyspepsia (indigestion), Decreased appetite, Hyperhidrosis (abnormally increased sweating), Ejaculation failure, Enuresis (bed-wetting), Hyperprolactinemia (abnormally high levels of prolactin in the blood), Menstrual irregularities, Pulmonary hypertension (increased blood pressure in the arteries of the lungs), Acute renal (kidney) failure, SIADH (Syndrome of Inappropriate Antidiuretic Hormone Secretion), Blindness, Cataract (cloudy area in the lens of the eye that leads to a decrease in vision), Agranulocytosis (severe and dangerous lowered white blood cell count), Edema, Gait disturbance, Irritability, Pyrexia (fever), Elevated liver enzymes, Anaphylaxis, Diabetes mellitus, Hypercholesterolemia (high cholesterol), Hypoglycemia (low blood sugar), Increased appetite, Arthralgia (joint pain), Muscle spasms, Tightness, Twitching, Ataxia (lack of voluntary coordination of muscle movements), Coma, Decreased alertness, Hypoesthesia (numbness), Hematuria (presence of blood or red blood cells in the urine), Galactorrhea (spontaneous flow of milk from the breast), Vaginal hemorrhage, Priapism (penis remains erect for hours in the absence of stimulation or after stimulation has ended), Alopecia (balness), Dermatitis bullous (inflammatory lesion of the skin with the formation of fluid), Pruritus (itchiness), Purpura (red/purple spots), Convulsion, Lethargy (state of tiredness, sleepiness, weariness, fatigue, sluggishness or lack of energy), Psychomotor hyperactivity (mood disorders), Syncope (fainting), Aggression, Bruxism (excessive teeth grinding or jaw clenching), Confusional state, Euphoric mood, Hallucination, Bronchospasm (sudden constriction of the muscles in the walls of the bronchioles), Epistaxis (nosebleed), Yawning, Cold sweat, Dermatitis, Hemorrhage (bleeding from a damaged blood vessel), Hypertension (high blood pressure), Vasodilation (widening of blood vessels), Erythematous (skin redness), Follicular/maculopapular rash, Urticaria (hives). Indication-specific adverse reactions: MDD: somnolence; OCD: insomnia, agitation; PD: constipation, agitation; PTSD: fatigue; PMDD: somnolence, dry mouth, dizziness, fatigue, and abdominal pain; SAD: insomnia, dizziness, fatigue, dry mouth, malaise.

Need more info? Click the link below for a helpful infographic you can view + save on your device.

---

---

Looking for Zoloft alternatives? Here are some to research.

Disclaimer: This guide is for informational purposes only. By providing the information contained herein we are not diagnosing, treating, curing, mitigating, or preventing any type of disease or medical condition. Before beginning any type of natural, integrative or conventional treatment regimen, it is advisable to seek the advice of a licensed healthcare professional. May contain affiliate links. Product photos/descriptions provided by company websites. This is not medical advice.